How to Choose a Joint Supplement
If you’re looking at joint supplements for early knee pain, arthritis or stiffness, here’s something useful to know:
A large double-blind clinical trial tested three options over 3 months:
- Glucosamine + chondroitin
- Glucosamine + chondroitin with MSM
- Placebo
The result was clear:
- Glucosamine + chondroitin alone didn’t meaningfully improve pain or function
- Adding MSM led to real reductions in pain and stiffness, starting as early as 4 weeks
- Improvements continued through 12 weeks
- Placebo performed worst (as expected)
What this means for you:
- Don’t judge a joint supplement by “glucosamine + chondroitin” alone
- Look for joint supplements that include MSM - it appears to be a key ingredient
- Early joint issues respond better than advanced arthritis
- Give it at least 8–12 weeks before deciding if it works
Smart checklist when choosing a joint supplement:
- Includes MSM (not optional)
- Uses clinically relevant doses
- Targets pain and stiffness, not just “joint health”
- Avoids relying on one or two ingredients
Bottom line: multi-ingredient formulas tend to outperform basic blends.
If MSM isn’t listed, it’s probably not doing much.
Check our Complete Joint Care - formulated by science, with these ingredients:
- Hydrolysed Collagen Peptides (Bovine)
- Glucosamine Sulphate NaCl (Shellfish)
- Methylsulphonylmethane (MSM)
- Magnesium Citrate
- Chondroitin Sulphate (Shark)
- Turmeric (95% Curcuminoids), A
- Vitamin C
- Vitamin D3
- Black Pepper




