benefits of msm

How to Choose a Joint Supplement

If you’re looking at joint supplements for early knee pain, arthritis or stiffness, here’s something useful to know:

A large double-blind clinical trial tested three options over 3 months:

  1. Glucosamine + chondroitin
  2. Glucosamine + chondroitin with MSM
  3. Placebo

The result was clear:

  • Glucosamine + chondroitin alone didn’t meaningfully improve pain or function
  • Adding MSM led to real reductions in pain and stiffness, starting as early as 4 weeks
  • Improvements continued through 12 weeks
  • Placebo performed worst (as expected)

What this means for you:

  • Don’t judge a joint supplement by “glucosamine + chondroitin” alone
  • Look for joint supplements that include MSM - it appears to be a key ingredient
  • Early joint issues respond better than advanced arthritis
  • Give it at least 8–12 weeks before deciding if it works

Smart checklist when choosing a joint supplement:

  • Includes MSM (not optional)
  • Uses clinically relevant doses
  • Targets pain and stiffness, not just “joint health”
  • Avoids relying on one or two ingredients

Bottom line: multi-ingredient formulas tend to outperform basic blends.

If MSM isn’t listed, it’s probably not doing much.

Check our Complete Joint Care - formulated by science, with these ingredients:

  • Hydrolysed Collagen Peptides (Bovine)
  • Glucosamine Sulphate NaCl (Shellfish)
  • Methylsulphonylmethane (MSM)
  • Magnesium Citrate
  • Chondroitin Sulphate (Shark)
  • Turmeric (95% Curcuminoids), A
  • Vitamin C
  • Vitamin D3
  • Black Pepper
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